Indianapolis, Indiana, is more than just the home of the Indy 500 and a thriving downtown scene—it’s also a city filled with distinctive hotels that blend history, art, and modern comfort. From boutique stays in historic buildings to luxury accommodations with local flair, these 7 unique hotels in Indianapolis offer memorable experiences for every traveler.
Whether staying downtown for a business trip or exploring the city’s arts and culture scene, these unique hotels in Indianapolis, Indiana, offer something for every traveler. From the historic elegance of the Bottleworks Hotel to the modern comfort of Homewood Suites IUPUI, each property captures the spirit of the city—creative, welcoming, and full of character.
1. Bottleworks Hotel
Address: 850 Massachusetts Ave, Indianapolis, IN 46204
Located in the heart of the vibrant and totally hip Mass Ave Arts District, the Bottleworks Hotel is a stunning example of Art Deco architecture and modern luxury. Once part of the historic Coca-Cola bottling plant, this boutique hotel combines industrial charm with contemporary design. Guests can enjoy spacious rooms with pretty bathrooms, vintage-inspired décor, and access to the nearby Bottleworks District’s restaurants, bars, and entertainment venues, including The Garage Food Hall.
I’ve had the pleasure of staying the night at Bottleworks, and it was a truly unique visit.
2. Ironworks Hotel Indy
Address: 2721 E 86th St, Indianapolis, IN 46240
The Ironworks Hotel Indy brings a rustic-industrial vibe to the north side of Indianapolis. Inspired by 19th-century factories, this boutique hotel features gorgeously exposed brick walls, reclaimed wood, and steel accents. Each room is uniquely designed with a mix of vintage and modern furnishings. The hotel’s location near Keystone at the Crossing makes it ideal for both business and leisure travelers.
As for onsite dining, you’ll have your choice of Provision and Blue Sushi Sake Grill, and on pretty weather days, a rooftop terrace to check out the city views.
3. The Alexander, a Dolce by Wyndham Hotel
Address: 333 S Delaware St, Indianapolis, IN 46204
Alexander is a modern art lover’s dream. Located in downtown Indianapolis, this hotel doubles as an art gallery, featuring over 200 works curated by the Indianapolis Museum of Art. The sleek, contemporary design and creative atmosphere make it one of the most unique hotels in Indianapolis. Guests can enjoy locally inspired cuisine at Plat 99, the hotel’s craft cocktail lounge designed by artist Jorge Pardo.
It’s only a short walk to both Gainbridge Fieldhouse and Lucas Oil Stadium
4. Nestle Inn
Address: 637 N East St, Indianapolis, IN 46202
For travelers seeking a cozy, bed-and-breakfast experience, the Nestle Inn offers a charming retreat just steps from Mass Ave. This historic inn blends old-world charm with modern convenience, featuring six individually decorated rooms with private baths. Guests can enjoy self-serve breakfast options and easy access to local restaurants, theaters, and shops.
Fun note: Nestle Inn is locally owned and operated, offers complimentary wi-fi and parking, and gives each guest a personalized experience.
5. Conrad Indianapolis
Address: 50 W Washington St, Indianapolis, IN 46204
The Conrad Indianapolis is a five-star luxury hotel that combines elegance with artistic flair. Located in the heart of downtown, it’s connected to the Indianapolis Artsgarden and Circle Centre Mall via skywalk. The hotel’s art-themed suites—dedicated to Modern, Contemporary, and Classic styles—make it a standout among luxury hotels in Indianapolis.
The Conrad is THE hotel to stay at if you want an amazing meal at The Capital Grille (carnivores love the steaks!) and a pampered time at the on-site spa.
6. Hotel Broad Ripple
Address: 6520 E Westfield Blvd, Indianapolis, IN 46220
Nestled along the Monon Trail in the Broad Ripple Village neighborhood, Hotel Broad Ripple offers a laid-back, boutique experience with a local touch. Each room is uniquely decorated, many featuring balconies overlooking the White River. The hotel’s rustic charm and proximity to local breweries, shops, and live music venues make it a favorite for weekend getaways.
When you stay, you’ll get complimentary breakfast, an outdoor patio and bar, and easy access to the Monon Trail.
7. Homewood Suites by Hilton Indianapolis IUPUI
Address: 414 W Vermont St, Indianapolis, IN 46202
Homewood Suites by Hilton Indianapolis IUPUI offers a comfortable and convenient stay near the Indiana University–Purdue University Indianapolis campus and downtown attractions. This extended-stay hotel features spacious suites with full kitchens, making it ideal for families, business travelers, and long-term guests. Its location near White River State Park, the Indianapolis Zoo, and the Indiana State Museum provides easy access to some of the city’s top destinations.
I’ve stayed here, and the fact that the lobby area is a desanctified church is truly unique. Additionally, the complimentary breakfast is spot on, and you can feel free to bring your furry friend - it’s pet-friendly!
